Identification of novel predictive biomarkers in patients with aneurysmal subarachnoid hemorrhage

Abstract

Acute stroke is a leading cause of death and one of the most common causes of permanent disability worldwide. In our country around 26,000 stroke cases occur each year, placing a significant burden on both healthcare and society, the two major categories of stroke (hemorrhage and ischemia) are the opposite conditions. Ischemic stroke accounts for approximately 80-85%of all stroke cases, while hemorrhage is responsible for the remaining 15-20%. Each of these categories can be divided into subtypes that have somewhat different causes, clinical pictures, clinical courses, outcomes, and treatment strategies. Intracranial hemorrhage can be caused by intracerebral hemorrhage (ICH, also called parenchymal hemorrhage), which involves bleeding into brain tissue, and subarachnoid hemorrhage (SAH), which involves bleeding into the cerebrospinal fluid that surrounds the brain and spinal cord and subdural, epidural hemorrhage.